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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1971 1
1973 1
1975 1
1977 3
1978 1
1979 4
1980 6
1981 2
1982 4
1983 11
1984 23
1985 17
1986 26
1987 40
1988 39
1989 55
1990 73
1991 82
1992 88
1993 105
1994 111
1995 116
1996 136
1997 121
1998 107
1999 131
2000 128
2001 116
2002 108
2003 125
2004 119
2005 130
2006 139
2007 136
2008 109
2009 124
2010 123
2011 110
2012 127
2013 129
2014 142
2015 119
2016 109
2017 91
2018 109
2019 100
2020 89
2021 105
2022 87
2023 63
2024 33

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3,779 results

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Page 1
Induction and Genomic Analysis of a Lysogenic Phage of Hafnia paralvei.
Pan L, Li D, Tong Y, Lin W, Qin W, Xu L, Zhan P. Pan L, et al. Curr Microbiol. 2022 Jan 4;79(2):50. doi: 10.1007/s00284-021-02698-0. Curr Microbiol. 2022. PMID: 34982243
Hafnia phage yong1 contains a tRNA gene and 76 predicted open reading frames, 33 of which were annotated. Gene strings similar to the bacteriophage lambda cro-cI-rexA-rexB operon conferring Imm and Rex to lysogenic cells were found in Hafnia phage yong1 genome. ...
Hafnia phage yong1 contains a tRNA gene and 76 predicted open reading frames, 33 of which were annotated. Gene strings similar …
Programmed drug-dependent ribosome stalling.
Ramu H, Mankin A, Vazquez-Laslop N. Ramu H, et al. Mol Microbiol. 2009 Feb;71(4):811-24. doi: 10.1111/j.1365-2958.2008.06576.x. Epub 2008 Nov 30. Mol Microbiol. 2009. PMID: 19170872 Free article. Review.
This fundamental property of the ribosome is often exploited in regulation of gene expression, in particular, for activation of expression of genes conferring resistance to ribosome-targeting antibiotics. Induction of expression of these genes is controlled by the programm …
This fundamental property of the ribosome is often exploited in regulation of gene expression, in particular, for activation of expression o …
SARS-CoV-2 ORF10 antagonizes STING-dependent interferon activation and autophagy.
Han L, Zheng Y, Deng J, Nan ML, Xiao Y, Zhuang MW, Zhang J, Wang W, Gao C, Wang PH. Han L, et al. J Med Virol. 2022 Nov;94(11):5174-5188. doi: 10.1002/jmv.27965. Epub 2022 Jul 7. J Med Virol. 2022. PMID: 35765167 Free PMC article.
Here, we screened 29 SARS-CoV-2-encoded viral proteins to explore the viral proteins that affect the cGAS-STING signaling pathway and found that SARS-CoV-2 open reading frame 10 (ORF10) targets STING to antagonize IFN activation. Overexpression of ORF10 inhibits cGA …
Here, we screened 29 SARS-CoV-2-encoded viral proteins to explore the viral proteins that affect the cGAS-STING signaling pathway and found …
Ubiquitination of SARS-CoV-2 NSP6 and ORF7a Facilitates NF-κB Activation.
Nishitsuji H, Iwahori S, Ohmori M, Shimotohno K, Murata T. Nishitsuji H, et al. mBio. 2022 Aug 30;13(4):e0097122. doi: 10.1128/mbio.00971-22. Epub 2022 Jul 20. mBio. 2022. PMID: 35856559 Free PMC article.
Here, we screened severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genes and found that nonstructural protein 6 (NSP6) and open reading frame 7a (ORF7a) activated the NF-kappaB pathway. NSP6 and ORF7a interacted with transforming growth factor beta-activ …
Here, we screened severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genes and found that nonstructural protein 6 (NSP6) and open …
C Proteins: Controllers of Orderly Paramyxovirus Replication and of the Innate Immune Response.
Siering O, Cattaneo R, Pfaller CK. Siering O, et al. Viruses. 2022 Jan 12;14(1):137. doi: 10.3390/v14010137. Viruses. 2022. PMID: 35062341 Free PMC article. Review.
These proteins, termed "C", are basic, have low amino acid homology and some secondary structure conservation. C proteins are encoded in alternative reading frames of the phosphoprotein gene. Some viruses express nested sets of C proteins that exert their functions …
These proteins, termed "C", are basic, have low amino acid homology and some secondary structure conservation. C proteins are encoded in alt …
The Cdkn2a gene product p19 alternative reading frame (p19ARF) is a critical regulator of IFNbeta-mediated Lyme arthritis.
Li J, Ma Y, Paquette JK, Richards AC, Mulvey MA, Zachary JF, Teuscher C, Weis JJ. Li J, et al. PLoS Pathog. 2022 Mar 24;18(3):e1010365. doi: 10.1371/journal.ppat.1010365. eCollection 2022 Mar. PLoS Pathog. 2022. PMID: 35324997 Free PMC article.
Small interfering RNA (siRNA)-mediated silencing identified Cdkn2a as the gene responsible for Bbaa1 allele-regulated induction of IFNbeta and IFN-stimulated genes (ISGs) in bone marrow-derived macrophages (BMDMs). The Cdkn2a-encoded p19 alternative reading frame …
Small interfering RNA (siRNA)-mediated silencing identified Cdkn2a as the gene responsible for Bbaa1 allele-regulated induction of IF …
[Mutation-specific treatments for Duchenne muscular dystrophy].
Matsuo M, Takeshima Y. Matsuo M, et al. Brain Nerve. 2009 Aug;61(8):915-22. Brain Nerve. 2009. PMID: 19697880 Review. Japanese.
Two promising treatments strategies have been proposed specifically for correcting the mutations in the dystrophin gene. Induction of exon skipping using antisense oligonucleotides is expected to correct the out-of-frame mutation into in-frame mutation of the …
Two promising treatments strategies have been proposed specifically for correcting the mutations in the dystrophin gene. Induction of …
Hepatitis E virus inhibits type I interferon induction by ORF1 products.
Nan Y, Yu Y, Ma Z, Khattar SK, Fredericksen B, Zhang YJ. Nan Y, et al. J Virol. 2014 Oct;88(20):11924-32. doi: 10.1128/JVI.01935-14. Epub 2014 Aug 6. J Virol. 2014. PMID: 25100852 Free PMC article.
In this study, we found that HEV replication in hepatoma cells inhibited poly(I.C)-induced beta interferon (IFN-beta) expression and that the HEV open reading frame 1 (ORF1) product was responsible for this inhibition. ...This is the first report of identification o …
In this study, we found that HEV replication in hepatoma cells inhibited poly(I.C)-induced beta interferon (IFN-beta) expression and that th …
Induction of an Alternative mRNA 5' Leader Enhances Translation of the Ciliopathy Gene Inpp5e and Resistance to Oncolytic Virus Infection.
Hoang HD, Graber TE, Jia JJ, Vaidya N, Gilchrist VH, Xiang X, Li W, Cowan KN, Gkogkas CG, Jaramillo M, Jafarnejad SM, Alain T. Hoang HD, et al. Cell Rep. 2019 Dec 17;29(12):4010-4023.e5. doi: 10.1016/j.celrep.2019.11.072. Cell Rep. 2019. PMID: 31851930 Free article.
We find that viral infection induces the expression of an Inpp5e mRNA variant that lacks repressive upstream open reading frames (uORFs) within its 5' leader and is efficiently translated. ...
We find that viral infection induces the expression of an Inpp5e mRNA variant that lacks repressive upstream open reading frames …
3,779 results